Protease-Activated Receptor-4 diTFA
CAS No. ——
Protease-Activated Receptor-4 diTFA( —— )
Catalog No. M21052 CAS No. ——
Protease-Activated Receptor-4 diTFA2454 is the proteinase-activated receptor-4 (PAR4)agonist.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 61 | Get Quote |
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| 5MG | 85 | Get Quote |
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| 10MG | 154 | Get Quote |
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| 25MG | 315 | Get Quote |
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| 50MG | 472 | Get Quote |
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| 100MG | Get Quote | Get Quote |
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| 200MG | Get Quote | Get Quote |
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| 500MG | Get Quote | Get Quote |
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| 1G | Get Quote | Get Quote |
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Biological Information
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Product NameProtease-Activated Receptor-4 diTFA
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NoteResearch use only, not for human use.
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Brief DescriptionProtease-Activated Receptor-4 diTFA2454 is the proteinase-activated receptor-4 (PAR4)agonist.
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DescriptionProtease-Activated Receptor-4 diTFA2454 is the proteinase-activated receptor-4 (PAR4)agonist.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayGPCR/G Protein
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TargetPAR
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RecptorPAR-4
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Research Area——
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Indication——
Chemical Information
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CAS Number——
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Formula Weight894.81
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Molecular FormulaC37H48F6N8O11
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Purity>98% (HPLC)
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Solubility——
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SMILESOC(=O)C(F)(F)F.OC(=O)C(F)(F)F.NCCCC[C@H](NC(=O)CNC(=O)[C@@H]1CCCN1C(=O)[C@H](CC1=CC=C(O)C=C1)NC(=O)CN)C(=O)N[C@@H](CC1=CC=CC=C1)C(N)=O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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AY 77
AY 77 (Unk-Cha-Chg-NH2) is a potent and selective PAR2 agonist. AY 77 showed selectivity for Ca2+ and ERK1/2 signaling (ec50 value of Ca2+ release was 40 nM and ec50 value of ERK1/2 phosphorylation was 2 μM).
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FSLLRY-NH2
Selective PAR2 peptide antagonist. Reverses taxol-induced mechanical allodynia, heat hyperalgesia and PKC activation in ICR mice. Blocks ERK activation and collagen production in isolated cardiac fibroblasts. Also reduces symptoms in a mouse model of dermatophyte-associated itch.
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Atopaxar
A potent, reversible PAR-1 antagonist with IC50 of 19 nM; shows potent inhibitory effects on human platelet aggregation induced by thrombin and TRAP with IC50 of 64 nM and 31 nM, respectively.
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